Edited by A
Fajgelj and A Ambrus
The Royal Society of Chemistry, 2000 [ISBN 0
85404 783 2]
This book is an overview of the most recent approaches used for
method validation in cases when a large number of analytes are
determined from a single aliquot and where a large number of samples
are to be analysed. Much of the content relates to the validation
of new methods for pesticide residue analysis in foodstuffs and
water but the principles can be applied to other similar fields
of analysis.
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Different chromatographic methods are discussed, including estimation
of various effects, eg. matrix-induced effects and the influence of
the equipment set-up. The methods used for routine purposes and the
validation of analytical data in the research and development environment
are documented. The legislation covering the EU-Guidance on residue
analytical methods, an extensive review of the existing in-house method
validation documentation and guidelines for single-laboratory validation
of analytical methods for trace-level concentrations of organic chemicals
are also included. With contributions from experts in the field, any
practising analyst dealing with method validation will find the examples
presented in this book a useful source of technical information.
This book contains lectures presented at the international workshop
on 'Principles
and Practices of Method Validation', held from 4 to 6 November 1999
in Budapest, Hungary. The International Association of Official Analytical
Chemists (AOAC International), Food and Agriculture Organisation (FAO),
International Atomic Energy Agency (IAEA), the International Union of
Pure and Applied Chemistry (IUPAC) and the Plant Health and Soil Conservation
Station of Budapest co-operated in the organisation of this event.
> Contents > Forward > Introduction > Ordering info available
onthe RSC website <http://www.rsc.org/is/books/methodval.htm>
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