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2003, Vol. 75, Issue 2-3
Special Topic Issue on the Theme of Natural Products

23rd IUPAC International Symposium on the Chemistry of Natural Products, Florence, Italy, 28 July–2 August 2002

This conference is part of the Natural Products series.
Inspirations from nature. New reactions, new therapeutic leads, and new drug delivery systems
P. A. Wender, J. L. Baryza, S. E. Brenner, M. O. Clarke, G. G. Gamber, J. C. Horan, T. C. Jessop, Cindy Kan, K. Pattabiraman and T. J. Williams
p. 143 [Details + Abstract] [Full text - pdf 324 kB]
Antiangiogenic heparin-derived heparan sulfate mimics
Benito Casu and A. Naggi
p. 157 [Details + Abstract] [Full text - pdf 382 kB]
Semisynthesis and degradation of the tubulin inhibitors epothilone and tubulysin
G. Höfle, N. Glaser, T. Leibold, U. Karama, F. Sasse and H. Steinmetz
p. 167 [Details + Abstract] [Full text - pdf 298 kB]
Synthesis of carbohydrate-based antibiotics
C.-H. Wong, M. C. Bryan, P. T. Nyffeler, H. Liu and Eli Chapman
p. 179 [Details + Abstract] [Full text - pdf 252 kB]
DNA minor-groove binders. Design, synthesis and biological evaluation of ligands structurally related to CC-1065, distamycin, and anthramycin
P. G. Baraldi, M. A. Tabrizi, D. Preti, Francesca Fruttarolo, Barbara Avitabile, Andrea Bovero, G. Pavani, M. Carmen Nunez del Carretero and R. Romagnoli
p. 187 [Details + Abstract] [Full text - pdf 197 kB]
HIV-1 integrase inhibitors that block HIV-1 replication in infected cells. Planning synthetic derivatives from natural products
Roberto Di Santo, Roberta Costi, Marino Artico, E. Tramontano, P. La Colla and A. Pani
p. 195 [Details + Abstract] [Full text - pdf 560 kB]
New and old challenges in total synthesis. From concept to practice
S. Hanessian, Roberto Margarita, Adrian Hall, Shawn Johnstone, M. Tremblay and L. Parlanti
p. 209 [Details + Abstract] [Full text - pdf 329 kB]
Chemoenzymatic methods for the enantioselective preparation of sesquiterpenoid natural products from aromatic precursors
M. G. Banwell, A. J. Edwards, G. J. Harfoot, K. A. Jolliffe, M. D. McLeod, K. J. McRae, S. G. Stewart and M. Vögtle
p. 223 [Details + Abstract] [Full text - pdf 210 kB]
Total synthesis of (­)-clavukerin A
E. L. Grimm, J.-L. Methot and M. Shamji
p. 231 [Details + Abstract] [Full text - pdf 170 kB]
Progress in fumagillin synthesis
W. Picoul, O. Bedel, A. Haudrechy and Y. Langlois
p. 235 [Details + Abstract] [Full text - pdf 483 kB]
Total syntheses of 11-deoxytetrodotoxin and 8,11-dideoxytetrodotoxin
T. Nishikawa, D. Urabe, K. Yoshida, Tomoko Iwabuchi, Masanori Asai and M. Isobe
p. 251 [Details + Abstract] [Full text - pdf 265 kB]
Biomimetic approach toward the stereoselective synthesis of acetogenins
R. V. A. Orru, Bas Groenendaal, J. van Heyst, Mark Hunting, C. Wesseling, R. F. Schmitz, S. F. Mayer and K. Faber
p. 259 [Details + Abstract] [Full text - pdf 202 kB]
Microencapsulated methylrhenium trioxide (MTO)/H2O2 systems for the oxidation of cardanol derivatives
R. Saladino, E. Mincione, O. A. Attanasi and Paolino Filippone
p. 265 [Details + Abstract] [Full text - pdf 226 kB]
Enantioselective synthesis and biological evaluation of a-hydroxylated lactone lignans
M. Sefkow, M. Raschke and C. Steiner
p. 273 [Details + Abstract] [Full text - pdf 299 kB]
Stereocontrolled construction of conformationally constrained and rigid bis(a-amino acid) derivatives
K. Undheim, Jon Efskind and G. B. Hoven
p. 279 [Details + Abstract] [Full text - pdf 413 kB]
Stereochemical analysis of natural products. Approaches relying on the combination of NMR spectroscopy and computational methods
R. Riccio, Giuseppe Bifulco, Paola Cimino, Carla Bassarello and Luigi Gomez-Paloma
p. 295 [Details + Abstract] [Full text - pdf 337 kB]
Exploitation of proteomics strategies in protein structure-function studies
Gennaro Marino, P. Pucci, Leila Birolo and M. Ruoppolo
p. 309 [Details + Abstract] [Full text - pdf 736 kB]
Prion protein allotype profiling by mass spectrometry
M. E. Schininà, Bruno Maras, Franco Cardone, Carmine Mancone, S. Principe, M. A. Di Bari, P. Parchi and M. Pocchiari
p. 317 [Details + Abstract] [Full text - pdf 206 kB]
Toxins from Adriatic blue mussels. A decade of studies
Patrizia Ciminiello, Carmela Dell'Aversano, Ernesto Fattorusso, Martino Forino and Silvana Magno
p. 325 [Details + Abstract] [Full text - pdf 264 kB]
Bioactive macrolides and polyketides from marine dinoflagellates
J. Kobayashi, K. Shimbo, Takaaki Kubota and M. Tsuda
p. 337 [Details + Abstract] [Full text - pdf 243 kB]
Detection of pharmacologically active natural products using ecology. Selected examples from Indopacific marine invertebrates and sponge-derived fungi
P. Proksch, R. Ebel, R. A. Edrada, P. Schupp, W. H. Lin, Sudarsono, V. Wray and K. Steube
p. 343 [Details + Abstract] [Full text - pdf 197 kB]
Chemical studies on plant leaf movement controlled by a biological clock
M. Ueda, T. Sugimoto, Y. Sawai, T. Ohnuki and Shosuke Yamamura
p. 353 [Details + Abstract] [Full text - pdf 449 kB]
Structural flexibility of hyaluronan oligomers as probed by molecular modelling
A. Tafi, Fabrizio Manetti, F. Corelli, Stefano Alcaro and M. Botta
p. 359 [Details + Abstract] [Full text - pdf 223 kB]
Functional genomics approach to the study of triterpene biosynthesis
Yutaka Ebizuka, Yuji Katsube, T. Tsutsumi, Tetsuo Kushiro and M. Shibuya
p. 369 [Details + Abstract] [Full text - pdf 207 kB]
Mevalonate-independent methylerythritol phosphate pathway for isoprenoid biosynthesis. Elucidation and distribution
M. Rohmer
p. 375 [Details + Abstract] [Full text - pdf 265 kB]
Biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum
L. Ning, Hongzhu Guo, Xiaomei Jiang, Kaishun Bi and Dean Guo
p. 389 [Details + Abstract] [Full text - pdf 167 kB]
The deoxyxylulose phosphate pathway of isoprenoid biosynthesis. Discovery and function of the ispDEFGH genes and their cognate enzymes
F. Rohdich, Stefan Hecht, Adelbert Bacher and Wolfgang Eisenreich
p. 393 [Details + Abstract] [Full text - pdf 281 kB]
Natural and totally synthetic receptors in the innovative design of HPLC chiral stationary phases
Francesco Gasparrini, Ilaria D'Acquarica, D. Misiti, M. Pierini and C. Villani
p. 407 [Details + Abstract] [Full text - pdf 189 kB]
Combination of enzymatic procedures with multicomponent condensations
R. Ostaszewski, D. E. Portlock, Anna Fryszkowska and Katarzyna Jeziorska
p. 413 [Details + Abstract] [Full text - pdf 171 kB]