Pure Appl. Chem., 2005, Vol. 77, No. 7, pp. 1251-1257
http://dx.doi.org/10.1351/pac200577071251
Combinatorial approach to the discovery of chiral catalysts for asymmetric reactions
Abstract:
The powerfulness of a combinatorial approach in the discovery of novel chiral catalyst systems, particularly for the development of highly efficient, enantioselective, and practical catalysts for asymmetric reactions, was demonstrated by screening modular chiral catalyst libraries created by the strategy of two-component ligand modification of metal ions on the basis of molecular recognition and assembly.
Keywords
asymmetric catalysis; combinatorial chemistry; hetero-Diels-Alder reaction; titanium; zinc.