Title: Pesticide Residues in Food: Acute Dietary Exposure
Chairman: D. Hamilton
A. Ambrus, A.
Felsot, R. Gonzalez,
C. Harris, H.
Kuiper, B. Petersen,
S. Reynolds, K.
Racke, Sue-Sun Wong
Completion Date: 2003 - project completed
To propose data requirements and methods of evaluation suitable for
estimating the acute dietary exposure of pesticide residues in food.
Problem Statement - Although human dietary exposure assessment
of pesticide residues has been of interest for some time, the focus
of current assessment schemes is on lifetime dietary consumption of
average residue levels. These schemes are relied upon by international
advisory bodies, national government agencies, the food industry, and
private industry for the evaluation of the safety of food residues resulting
from both currently approved pesticide uses and those that may result
from proposed or future uses. Results of monitoring data indicate that
pesticide residue levels in individual units/servings of fruit or vegetables,
that may be consumed at a single meal or during a single day, may vary
considerably from the average residue level. For acutely toxic pesticide
residues, this has raised concerns that current dietary exposure assessment
schemes may not be adequate for protection of public health. At present,
there is a lack of standardized approaches for international and national
acute dietary exposure assessment for pesticide residues as well as
clear definition of the data requirements for such schemes.
Methodology - The project will examine available field residue
trial and monitoring data on the distribution of pesticide residues
in individual fruits and vegetables. Data sources will include the peer-reviewed
published literature, reports from government monitoring programs, and
proprietary data generated by pesticide manufacturers and industry associations.
Information on the approaches being considered or developed by research
groups and national regulatory agencies will be collected and assessed.
The utility and data requirements of both deterministic and probabilistic
approaches to exposure assessment will be evaluated. The final work
product will be a proposed set of data requirements and standardized
methods for evaluation of the acute dietary exposure of pesticide residues
Following development of a preliminary workplan by the Task Group, a
workshop will be held to review available data and current approaches,
seek input on the specific needs of the customer/client groups, and
generate a final workplan for the Task Group.
Hamilton, D.; Ambrus, A.; Dieterle, R.; Felsot, A.; Harris, C.; Petersen,
P.; Racke, K.; Wong, S-S., Gonzalez, R.; Tanaka, K. ; Earl, M.; Roberts,
G.; Bhula, R. Pesticide Residues in Food:
Acute Dietary Exposure. Pest Management Science 60, April
2004, vol. 60, no. 4, pp. 311-339(29) .
Last Update: 13 July 2005