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Vol. 25 No. 3
May - June 2003

The Project Place | Information about new, current, and complete IUPAC projects and related initiatives
See also www.iupac.org/projects

Solubility of Hydroxybenzoic Acids and Hydroxybenzoates

Hydroxybenzoic acids and related compounds are pharmaceutically important substances. In particular, 2-hydroxybenzoic acid has been widely used as a medicine and a preservative for food products; 4- hydroxybenzoic acid alkyl esters have also been used as preservatives for food. The relation between the use of these substances and human health requires evaluation of the solubilities of 2-, 3-, and 4-monohydroxybenzoic acids and of 4-hydroxybenzoic acid alkyl esters in water, organic and mixed solvents. In this project, it is also intended to evaluate the solubilities of (a) 2- and 3-hydroxybenzoic acid in supercritical carbon dioxide containing organic solvents such as methanol and acetone, and (b) monohydroxybenzoates, 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5- dihydroxybenzoic acid salts of alkali, transition, and rare earth metals in water and organic solvents.

www.iupac.org/projects/2002/2002-036-1-500.html


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