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Organizations & People
Release, 30 October 2003
SCOPE / IUPAC Report
Endocrine Active Substances
A report from the Scientific Committee on Problems of the Environment
(SCOPE) and International Union of Pure and Applied Chemistry (IUPAC)
project on endocrine active substances, a major project looking
at these potentially harmful substances from a world-wide perspective,
will be published in a double issue of the IUPAC Journal, Pure
and Applied Chemistry, 75 (11/12), 2003, edited by J.
Miyamoto and J. Burger. An Executive Summary is available
on the IUPAC website at www.iupac.org/publications/pac/2003/7511/.
The Executive Summary wil be sent to the IUPAC National Adhering
Organizations, Associate National Adhering Organizations, and Company
Associates, as well as major chemical societies and other interested
organizations throughout the world.
The SCOPE/IUPAC project Environmental
implications of endocrine active substances: Present state-of-the-art
and future research needs was initiated during 2000 and
culminated at a Symposium held 1721 November 2002 in Yokohama,
Japan, where 408 individuals from 31 countries gathered. Scientists,
managers, and public policy-makers presented papers on human effects,
wildlife effects, exposure assessment, and testing for endocrine
active substances and endocrine disruption effects. At the meeting,
a range of needs was identified that applies to all aspects of the
study of endocrine disruption and endocrine active substances. The
in-depth, comprehensive, authoritative review of endocrine active
substances and their environmental and health effects by this project
will facilitate risk assessment and assist governmental and intergovernmental
authorities, industry, and the wider public in framing policies
and establishing research directions to address these issues.
We have learned during the past decade that the global effects attributed
to endocrine active substances are not as all pervading or fearsome
as some have asserted. There are, however, sufficient examples and
biological plausibility to leave little basis for complacency in
the research community. Future well-designed research will elucidate
the magnitude of the problem, identify target substances of concern,
and advance our knowledge of human and wildlife health. In addition
to overall conclusions regarding the present state of knowledge,
a series of more than 40 specific research recommendations was developed
to assist future efforts.
More information about SCOPE is available at <www.icsu-scope.org>.
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