Pure Appl. Chem., 2006, Vol. 78, No. 2, pp. 441-449
http://dx.doi.org/10.1351/pac200678020441
New synthetic reactions catalyzed by cobalt complexes
Abstract:
Without suffering from β-elimination, cobalt complexes allow cross-coupling reactions of alkyl halides with Grignard reagents. A combination of a cobalt complex and trimethylsilylmethyl Grignard reagent effects Mizoroki-Heck-type reaction of alkyl halide with styrene, which conventional palladium catalysts have never made possible. Cobalt exhibits intriguing catalytic activities on hydrophosphination and allylzincation of alkynes. Silylmethylcobalt reagent is a powerful tool for the synthesis of highly silylated ethenes.
Keywords
cobalt; cross-coupling reactions; Grignard reagents; Mizoroki-Heck reactions; synthesis.