Pure Appl. Chem., 2007, Vol. 79, No. 2, pp. 269-279
http://dx.doi.org/10.1351/pac200779020269
Widening the usefulness of epoxides and aziridines in synthesis
Abstract:
Deprotonation of terminal epoxides and aziridines with organolithium/diamine combinations or lithium amides allows the regio- and stereoselective formation of α-lithiated species. Judicious choice of reaction conditions allows these species to operate as nucleophiles, enolate equivalents, vinyl cation equivalents, or carbenes.