Pure Appl. Chem., 2011, Vol. 83, No. 3, pp. 461-478
http://dx.doi.org/10.1351/PAC-CON-10-10-19
Published online 2011-01-29
1,5-Polyols: Challenging motifs for configurational assignment and synthesis
Abstract:
Despite the well-established methods for stereochemical assignments and synthesis of 1,3-diols, the corresponding 1,5-diols and -polyols present specific challenges which remain unsolved. This article highlights some new strategies and methodologies specifically designed for the 1,5-diol motif.
Keywords
alcohols; asymmetric synthesis; coupling reactions; natural products; polyketides.