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Vol. 26 No. 2
March-April 2004

The Project Place | Information about new, current, and complete IUPAC projects and related initiatives
See also www.iupac.org/projects

Post Genomic Chemistry

More than 20 specialists from 11 countries (Belgium, Canada, Estonia, France, Germany, Italy, Poland, Russia, Sweden, UK, and USA) actively participated in an interdisciplinary project on post genomic chemistry. In developing this project, scientists joined forces from the fields of structural chemistry, biopolymer science, synthetic chemistry, drug design, and bio-inorganic and bio-analytical chemistry.

These scientists prepared a technical project report, which has been submitted to Pure and Applied Chemistry for publication, based on their published research from the last two to three years in journals such as Nature, Science, Journal of American Chemical Society, Journal of Analytical Chemistry, Journal of Molecular Catalysis, and others.

In developing this project, a mini-workshop was held 6–8 September 2003 in Moscow, which allowed experts to exchange views on chemistry in the post genomic era. In particular, they discussed the implication of advances in genomics, proteomics, biomimetics, and biological and chemical informatics. Such advances involve combinatorial chemistry and automated chemical synthesis, synthesis of new classes of unnatural amino acids, development of new biosynthesis methods for preparation of proteins containing unnatural amino acids, chemical management of biosystems at the molecular level, and self-multiplying polymers.

In deciding on the project objectives, this group of scientists was influenced by a number of different conferences and seminars. Great interest was generated in particular by a plenary lecture on “Post Genomic Chemistry: New Possibilities and New Challenges” presented at the 17th International Mendeleev Congress on Pure and Applied Chemistry (September 2003, Kazan).

The development of this project revealed the necessity of creating new educational programs and training courses for chemistry students and faculty on the chemical basis of genomics. Such courses could include the chemical basis for genomic studies, genes and genomes for chemists, and bio- and chemo-informatics.

Financial support for the project was provided by IUPAC and the “Biocatalysis and Biocatalytical Technologies” project of the Ministry of Science and Technology of the Russian Federation.

For more information, contact the Task Group Chairman Sergey D. Varfolomeyev <sdvarf@enzyme.chem.msu.ru>.

www.iupac.org/projects/2001/2001-005-1-300.html


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