26 No. 5
Glossary of Terms Used in Toxicokinetics
(IUPAC Recommendations 2003)
by M. Nordberg, et. al.
Pure and Applied Chemistry
Vol. 76, No. 5, pp. 1033-1082 (2004)
Within the framework of IUPAC Division VII, Chemistry and Human Health, the project to develop a “Glossary for Toxicokinetics of Chemicals” was initiated in 2001. Like many IUPAC bodies, the division is devoted to promoting world-wide “regulation, standardization, or codification” of relevant areas of chemistry. Over the years, toxicology and toxicokinetics have grown rapidly in importance. Lack of knowledge and confusion in the terminology currently used in the field of toxicokinetics constitute a problem for the development of the subject. Accordingly, the aim of the project was to compile definitions of the current terminology used in toxicokinetics, including, where relevant, information on chemical speciation, analytical methods, analytical equipment, and biological activity of chemicals.
This glossary contains definitions of 365 terms frequently used in the multidisciplinary field of toxicokinetics. The glossary is compiled primarily for chemists who currently work in toxicology and require a knowledge of the expressions used in toxicokinetics, especially in relation to hazard and risk assessment. Some medical terms are included, where relevant, because of their frequent occurrence in the toxicological literature and because chemists would not normally be expected to be familiar with them. There are three annexes, one containing a list of abbreviations and acronyms used in toxicokinetics, one containing a list of abbreviations and acronyms of names of international bodies and legislation that are relevant to toxicology and chemical safety, and one giving sources for further reading.
last modified 1 September 2004.
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